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Evidence of impaired regulation of the opioid system in ME/CFS and fibromyalgia

A team of researchers including Prof. Jo NijsAssociate Prof. Andrea PolliJente Van Campenhout, and Jolien Hendrix – all of whom have all received research funding from ME Research UK – have published a paper in the International Journal of Molecular Sciences considering whether changes in gene activity that do not alter the DNA sequence itself (epigenetic modifications) could lead to dysregulation of a system central to pain regulation (the endogenous opioid system) in people with ME/CFS and fibromyalgia.

While this study is not directly funded by ME Research UK, the group used samples obtained during their previous ME Research UK-funded project.

You can read a summary of the new paper on our website.

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