Congratulations to Dr Krista Clarke on the publication of her doctoral thesis: “Characterising the Electrophysiological Properties of Cells in Health and Disease” – https://tinyurl.com/5n86js82
Note: Electrophysiology is the study of the electrical properties of biological cells and tissues.
Krista’s thesis presents three studies which used “high-throughput, non-invasive, and low-cost tools” to “examine the electrophysiological properties of two cell types, peripheral blood mononuclear cells (PBMCs) and chondrocytes, for novel medical applications.” She specifically explored the electrophysiological properties of PBMCs in ME/CFS; whether electrophysiological properties could show how well someone is protected against SARS-CoV-2 (COVID-19); and the electrophysiological properties of chondrocytes (cells responsible for cartilage formation).
The thesis mentions that the specialised techniques/methods used in the first study “differentiated ME/CFS donors from healthy controls with 81.80% sensitivity and 85.70% specificity. This shows potential as a quantitative diagnostic biomarker.”
Krista is a member of a team working on research jointly funded by ME Research UK and the ME Association – https://bit.ly/dorey066
