This year’s Big Give Christmas Challenge will run from midday Tuesday 2nd December to midday Tuesday 9th December 2025. Thanks to our Pledgers, the first £19,100 donated on the Big Give website will be DOUBLED.
The Big Give accept donations from £1 upwards.
How were Big Give 2024 funds invested?
Thanks to the generosity of Pledgers, donors, and The Big Give Charity Trust, ME Research UK received a total of £56,732 (excluding GiftAid) – which was 101% of our campaign target.
Every penny received was invested in ME research and has enabled us to fund a project with Dr Sarah Annesley at La Trobe University in Australia looking at microRNA profiles and their impact on platelet function and energy production in women with ME/CFS.


