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Genes involved in neurodevelopment are linked to ME/CFS

Prof. Brett Lidbury and colleagues at the Australian National University and other institutions published findings of their ME Research UK-funded study in June, analysing the whole-exome sequences of people with ME/CFS.

Variants in a number of genes were significantly associated with ME/CFS, compared with a matched population. These genes are involved in several processes in the brain – including the generation of new neurons in the cerebral cortex – and in the development of neuroblastoma, a type of cancer affecting the nerve tissue.

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