How many people have ME/CFS?
It’s said that 17 million people in the world have ME/CFS – but this figure is no more than a…
Exercise and gene expression
The cardinal symptom of ME in the historical literature was profound, post-exertional loss of muscle power associated with muscle pain,…
Exploding the myth of depression
The hypothesis that depression is at the root of the symptoms of ME/CFS – a myth particularly prevalent in the…
Inflammation of the brain
As you might expect, the journal Medical Hypotheses publishes speculative papers about the cause and consequences of diseases. Because it…
Herpesviruses revisited
Herpesviruses, such as Epstein–Barr virus (EBV) or human cytomegalovirus (HCMV), were once thought to have a central role in ME/CFS,…
Markers of immune function
Research into the immunological aspects of ME/CFS has been an ongoing quest for the past 25 years. Findings have included…
Does ME/CFS run in families?
While there is anecdotal evidence from ME/ CFS patients and carers that the illness can run in families – particularly…
Disability and school absence
Illness in youngsters has a particular poignancy, and it is sometimes forgotten that around 9,000 people under the age of…
Publication of the PACE trial
In the early 2000s, the UK’s Medical Research Council (MRC) funded two large clinical trials of ‘cognitive behavioural’ approaches for…
Cerebrospinal fluid proteins
ME/CFS shares its symptoms with a range of illnesses, a fact which will complicate diagnosis and research of the condition…
