‘Chronic overlapping pain conditions’, including ME/CFS, require ‘patient-centred’ care that brings different specialties together.

Many people with ME/CFS also live with other illnesses, such as fibromyalgia, irritable bowel syndrome (IBS), chronic migraine, endometriosis, or painful temporomandibular disorders. Because of this, a recent review study by Prof. Emmanuel d’Incau and colleagues is highly relevant. Their research reviewed the evidence surrounding what they termed “Chronic overlapping pain conditions” (COPCs)—defined as a […]

Disrupted brain waste clearance system in ME/CFS

Researchers Kiran Thapaliya, Sonya Marshall-Gradisnik, Maira Inderyas, Leighton Barnden Institution Griffith University, Gold Coast, Queensland, Australia Publication Frontiers in Neuroscience, 2026 June 19; 20:1875420 Funding This research was funded by ME Research UK (SCIO Charity Number SC036942) with the financial support of The Fred and Joan Davies Bequest Key findings About the study Dr Kiran […]

ME/CFS and general anaesthesia – study highlights that more research is needed to guide care for people with the disease

A team or researchers in Regensburg, Bavaria have highlighted the lack of research around general anaesthesia in people with ME/CFS. Stating that “robust clinical evidence to guide perioperative management or anaesthetic techniques in patients with ME/CFS remains lacking” and at present, care during and after surgery is largely delivered as “care as usual”, the researchers […]

Experiences of pacing with a heart rate monitor for ME/CFS

Pacing is a self-management technique that involves balancing activity and rest to try to prevent or reduce post-exertional malaise (PEM), the cardinal symptom of ME/CFS. While some people with ME/CFS use heart rate monitors, such as those built into smartwatches, to help them pace their activity levels, little is known about the experiences and attitudes […]

Researcher Circle – June 2026

On the 26th June 2026, the fifth meeting of ME Research UK’s Researcher Circle took place. In this session, Dr Alkisti Manousaki – Daphne Jackson Fellow at Leicester University, co-funded by ME Research UK and the Medical Research Council – spoke to the group about fellowship applications. Within the talk, Alkisti: Following the talk, the […]

Long term follow up of women with ME/CFS in Serbia

Researchers in Serbia have published a study following 40 women with ME/CFS –   diagnosed using the 2015 Institute of Medicine (IOM), now the National Academy of Medicine (NAM), criteria for the disease – up over a 16-year period.   The ‘longitudinal’ study aimed to: Findings suggested that among the group of women with ME/CFS, 85% […]

Hyperbaric oxygen therapy (HBOT) for ME/CFS: Yes, No, Maybe?

Hyperbaric oxygen therapy (HBOT) is a medical treatment where patients breathe pure oxygen inside a pressurised chamber. The higher-than-normal pressure forces more oxygen into the lungs and bloodstream, allowing it to be delivered to damaged or oxygen-deprived tissues to accelerate healing. Whilst HBOT is an established and effective treatment for conditions such as diabetic foot […]

Orexins and GLP-1s as they relate to long COVID and ME/CFS

A recent review highlighted the devastating multi-system effects of COVID on the body, particularly emphasising the endocrinological (hormonal) consequences manifesting in long COVID, and additionally ME/CFS in a proportion of people. The review honed in on the potential influences of chemical messenger orexin and glucagon-like peptide-1 (GLP-1) “another key player in metabolism”. Why Orexin? Orexins are neuropeptides […]

Analysis of protein signatures in the clear fluid that surrounds and cushions the brain and spinal cord, known as cerebrospinal fluid, in people with ME/CFS.

Researchers Dr Bo Bertilson, alongside colleagues Björn Bragée, Peng Li, Danielle Meadows, Anna Widgren, Per  Sjögren, Per Hamid Ghatan, Wenzhong Xiao and Jonas Berquist. Institution Bragée Clinics, Sweden Publication Bragée, B., Li, P., Meadows, D. et al. Proteomic signatures in cerebrospinal fluid and their clinical associations in patients with ME/CFS. Sci Rep 16, 15848 (2026). https://www.nature.com/articles/s41598-026-46965-1 Funding This work […]

ME Awareness week 2026 – Research into sleep difficulties

Poor sleep quality in people with ME/CFS has been linked with lower quality of life. Research into the underlying causes of sleep dysfunction in ME/CFS is limited, but suggests: Despite evidence of sleep dysfunction in ME/CFS, research into its underlying causes remains limited. Many studies use the Fukuda criteria for chronic fatigue syndrome (CFS), which do not […]

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