Principal investigator Dr Bhupesh Prusty Institution Julius Maximilian University of Würzburg Start date August 2021 Funding This project is funded by ME Research UK with the financial support of The Gordon Parish Charitable Trust. Background and aim Human herpesvirus 6 (HHV-6), human herpesvirus 7 and Epstein-Barr virus have all been implicated as potential infectious triggers […]
Principal investigator Dr Sarah Annesley Institution La Trobe University, Melbourne, Australia Start date June 2021 Funding This project is funded by ME Research UK with the financial support of The Fred and Joan Davies Bequest. Background and aim Dr Sarah Annesley and Prof. Paul Fisher are based at La Trobe University in Melbourne, Australia. This […]
Dr Eleanor Roberts explores the processes by which our body generates energy, and how these may be disrupted in people with ME/CFS. As anyone with ME/CFS can testify, the reason why people with the illness can’t do many everyday activities with the same ease with which they used to is that their muscles seem drained […]
Dr Eleanor Roberts Our previous article discussed mitochondria structure, function and metabolism; here we put some of that knowledge into the context of ME/CFS. As anyone with ME/CFS can testify, the reason you can’t lift, push or carry the things you once lifted, pushed or carried with ease is because your muscles seem drained of […]
Dr Eleanor Roberts Mitochondria are small organelles found in large quantities in almost all cells of the body. They are thought to have once been independent entities that joined forces with our single-celled ancestors as each organism was advantageous to the other. This is suspected as mitochondria have their own DNA and can, independently from […]
Cara Tomas and colleagues from Newcastle University have recently published a report on mitochondrial function in ME/CFS, and this study is related to research on muscle fatigue they are currently pursuing with support from ME Research UK. The mitochondria are considered the power plants of the body, generating the energy needed to support life, and […]
Authors Cara Tomas, Audrey E. Brown, Julia L. Newton, and Joanna L. Elson Institution Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK Abstract Abnormalities in mitochondrial function have previously been shown in chronic fatigue syndrome (CFS) patients, implying that mitochondrial dysfunction may contribute to the pathogenesis of disease. This study builds on previous […]
Mitochondria are often referred to as the power plants of the body because they are responsible for generating nearly all the energy needed to support life. These kidney bean-shaped structures are found in most cells and are made up of different compartments, each with a specific role related to the metabolism of the cell they […]
Mitochondria are found in most cells, and their main job is to generate chemical energy. Disorders of mitochondrial function are implicated in a number of diseases, including mental disorders and heart problems, as well as being involved in the ageing process. Since ME/CFS is characterised by a profound, generalised, post-exertional loss of muscle power, it […]
The mitochondria are small organelles (or subunits) found in most animal and plant cells. They are often described as the power plants of the cell because their main job is to generate chemical energy, although they also have other roles in signalling and cell growth. Mitochondrial dysfunction seems to be implicated in a number of […]
