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New project studying muscle microvascular pathology in ME/CFS

ME Research UK is delighted to announce that we have awarded funding to Dr Rob Wüst at Vrije Universiteit Amsterdam in the Netherlands for a new study aiming to study microvascular pathology in the muscle and blood of people with ME/CFS.

Dr Wüst made waves recently with his research which found multiple abnormalities in muscle structure and function in people with long COVID, as well as the presence of microscopic clots (microclots), which increased after an exercise test to induce post-exertional malaise (PEM).

Given the similarity in symptoms and potential link between ME/CFS and long COVID, could there be a similar picture in people with ME/CFS? This is the question Dr Wüst and colleagues want to answer in this new study in which they will assess muscle biopsy samples taken from people with ME/CFS before and after inducing PEM.

Their findings may help improve our understanding of PEM in ME/CFS, and possibly pave the way towards new therapies.

This project was made possible thanks to the generosity and fundraising of our supporters, including those who donated during 2023’s Big Give campaign.

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