What is Epstein-Barr Virus (EBV) and how is it related to ME/CFS? Many individuals with ME/CFS state that an episode of infectious mononucleosis, i.e. glandular fever, preceded the development of their ME/CFS. Hence, it is no surprise that Epstein-Barr virus (EBV), the virus that causes infectious mononucleosis, has generated much interest in ME/CFS research. How […]
Epstein-Barr virus (EBV) – which causes glandular fever (mononucleosis), has received much attention in ME/CFS research. While research has linked EBV to the onset of ME/CFS, less is known – particularly in young people, about what happens to symptoms and severity over time in ME/CFS following EBV infection. Therefore, authors of a recently published study […]
Nuno Sepúlveda and colleagues from a number of institutions (including Charité – Universitätsmedizin Berlin and the London School of Hygiene and Tropical Medicine) have recently published more results from their ME Research UK-funded study looking at whether antibody responses against Epstein-Barr virus can serve as biomarkers for ME/CFS. You can read a brief summary of […]
Researchers Nuno Sepúlveda, João Malato, Franziska Sotzny, Anna D Grabowska, André Fonseca, Clara Cordeiro, Luís Graça, Przemyslaw Biecek, Uta Behrends, Josef Mautner, Francisco Westermeier, Eliana M Lacerda & Carmen Scheibenbogen Institutes Warsaw University of Technology, Poland; Charité – Universitätsmedizin Berlin, Germany; London School of Hygiene and Tropical Medicine, UK; and others Publication Frontiers in Medicine, […]
Epstein-Barr virus (EBV) is extremely common and affects most people at some time over their lives. It has long been suggested as a trigger for ME/CFS, and we are currently funding research from Dr Nuno Sepúlveda and Prof. Carmen Scheibenbogen looking at this area. There is also considerable evidence suggesting that EBV is a causative […]
Principal investigators Dr Nuno Sepúlveda & Prof. Carmen Scheibenbogen Institutions London School of Hygiene & Tropical Medicine and Charité Universitätmedizin Berlin Start date October 2020 Funding This project is funded by ME Research UK with the financial support of The Fred and Joan Davies Bequest. Background and aim The emergence of so-called ‘long COVID’ has […]
Key points History of ME/CFS Medical doctor and research fellow, Dr Susan Levine, set the tone for the conference with an overview of the history of ME/CFS following various infectious outbreaks. She mentioned that the majority of ME/CFS cases are thought to be due to an acute viral illness but in a minority of cases […]
Overview A deeper look Both endothelial dysfunction (impaired function of blood vessel lining known as the endothelium) and herpesviruses are topics of interest in ME/CFS research, though studies linking these subject areas remains sparse. A review by researchers from Stellenbosch University, South Africa, explored whether a potential relationship between herpesvirus infection and endothelial dysfunction may […]
Additional findings from ME Research UK-funded studies Dr Leighton Barnden and his team at Griffith University have recently published more findings from their ME Research UK-funded study using advanced imaging techniques to look at brain abnormalities in people with ME/CFS. Dr Barnden explains more about his research in a short video. Dr Sarah Annesley and […]
Making waves in ME/CFS brain research ME Research UK-funded studies are contributing to invaluable progress in understanding the brain in ME/CFS. As discussed on his YouTube channel, Dr Jarred Younger is using a novel brain scan to look at leukocyte infiltration which could potentially lead to neuroinflammation. Dr Leighton Barnden’s study showing brainstem volume changes […]
