ME/CFS and Epstein-Barr Virus (EBV) – some facts

What is Epstein-Barr Virus (EBV) and how is it related to ME/CFS? Many individuals with ME/CFS state that an episode of infectious mononucleosis, i.e. glandular fever, preceded the development of their ME/CFS. Hence, it is no surprise that Epstein-Barr virus (EBV), the virus that causes infectious mononucleosis, has generated much interest in ME/CFS research. How […]

Revisiting EBV

Nuno Sepúlveda and colleagues from a number of institutions (including Charité – Universitätsmedizin Berlin and the London School of Hygiene and Tropical Medicine) have recently published more results from their ME Research UK-funded study looking at whether antibody responses against Epstein-Barr virus can serve as biomarkers for ME/CFS. You can read a brief summary of […]

Revisiting IgG antibody reactivity to EBV in ME/CFS and its potential application to disease diagnosis

Researchers Nuno Sepúlveda, João Malato, Franziska Sotzny, Anna D Grabowska, André Fonseca, Clara Cordeiro, Luís Graça, Przemyslaw Biecek, Uta Behrends, Josef Mautner, Francisco Westermeier, Eliana M Lacerda & Carmen Scheibenbogen Institutes Warsaw University of Technology, Poland; Charité – Universitätsmedizin Berlin, Germany; London School of Hygiene and Tropical Medicine, UK; and others Publication Frontiers in Medicine, […]

Analysing antibody responses against EBV-derived antigens in ME/CFS

Principal investigators Dr Nuno Sepúlveda & Prof. Carmen Scheibenbogen Institutions London School of Hygiene & Tropical Medicine and Charité Universitätmedizin Berlin Start date October 2020 Funding This project is funded by ME Research UK with the financial support of The Fred and Joan Davies Bequest. Background and aim The emergence of so-called ‘long COVID’ has […]

Cognitive dysfunction (brain fog) in ME/CFS

Cognitive dysfunction, often referred to as “brain fog”, is a complex and distressing core symptom of ME/CFS that encompasses issues with mentally processing, verbalising, and remembering information. The experience of cognitive dysfunction cannot be equated to the occasional forgetfulness and lapses in concentration experienced by healthy individuals. Rather, cognitive impairments in ME/CFS can fluctuate between […]

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