Experiments with laser-evoked potentials and cerebral blood flow
There is now good evidence of hypersensitivity of the central nervous system – called central sensitization – in ME/CFS patients. However, direct monitoring of brain responses to harmful (noxious) stimuli has never been performed in patients with ME/CFS, and such direct evidence of central sensitization is crucial if the scientific world is to be persuaded.
For this reason, ME Research UK has funded a consortium of researchers specialising in neurology, cardiology and rehabilitation at Vrije Universiteit Brussel – led by Prof. Jo Nijs who has been at the forefront of ME/CFS investigation for a number of years – to undertake two related studies. Both aim to unravel the abnormal response of people with ME/CFS to exercise and, specifically, the inability of the brain of these patients to activate pain inhibition during and after physical activity.
Read more at our project page Interrogating the Brain