Our heart rate normally increases when we exercise, but a new study from the University of the Pacific, in California, shows that this response is impaired in many people with ME/CFS. This phenomenon is known as chronotropic intolerance, and potentially provides further evidence of autonomic dysfunction in the illness (also seen in work by Prof. Newton in Newcastle). The authors suggest their findings also raise questions about the use of pacing to manage ME/CFS.

Read more at Frontiers in Pediatrics